Higher Scientific Officer - Molecular Cell Biology group

29th May 2026

Under the guidance of Marjan Iravani, we are seeking to appoint an enthusiastic, experienced Higher Scientific Officer to join the Isacke 'Molecular Cell Biology' laboratory. The main responsibility of the position is to conduct lab based and in-vivo experiments as part of a team developing CAR-T cells to support our work on developing new therapeutic strategies for a broad range of sarcoma subtypes both in primary and metastatic disease.

About You

The successful candidate must have:

• A BSc or equivalent in Biochemistry, Molecular Biology, Cell Biology or Immunology
• Proven degree of technical experience with a minimum of 3 years working in a research laboratory

Department/Directorate Information

The Molecular Cell Biology group led by Professor Clare Isacke is a multidisciplinary team of cell and molecular biologists and in-vivo specialists. A main interest (and focus of this HSO position) is in developing new antibody-based therapeutics (specifically CAR-T cells and ADCs) targeting the breast tumour microenvironment and a broad range of sarcoma subtypes. Our secondary interest is in the biology of the breast cancer metastatic microenvironment, particularly invasive lobular breast cancer metastasis.

This HSO position will be located in The Breast Cancer Now Toby Robins Research Centre at the ICR at our Chelsea site. The Breast Cancer Now Toby Robins Research Centre, within the Division of Breast Cancer Research at The Institute of Cancer Research is the first centre in the UK entirely devoted to breast cancer research. Its mission is to advance understanding of the causes, diagnosis and treatment of breast cancer. The Centre is housed in state-of-the-art laboratory space, with excellent core facilities and is funded through a long-term renewable programme grant from Breast Cancer Now. It is directed by Clinician Scientist Professor Andrew Tutt, with Professor Chris Lord as Deputy Director. The Centre has received major international recognition, including the 2022 AACR Team Science Award, shared with its breast cancer clinical research partners in the ICR’s Clinical Trials and Statistics Unit and The Royal Marsden Hospital. Its work also contributed to the ICR receiving the 2023 Queen’s Anniversary Prize for transforming lives through world-leading breast cancer research.

What We Offer

• A dynamic and supportive research environment
• Access to state-of-the-art facilities and professional development opportunities
• Collaboration with leading researchers in the field
• Competitive salary and pension

We encourage all applicants to access the job pack attached for more detailed information regarding this role.

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.