Clinical Research Fellow

Ref Number B02-10580 Professional Expertise Clinical Department School of Life & Medical Sciences (B02) 02-Jun-2026 About us We are one of the world’s leading research centres for the study of prions and their wider relevance to neurodegenerative disease with a growing research activity in Alzheimer’s disease (www.prion.ucl.ac.uk). The Institute is highly multidisciplinary with close integration of structural and molecular biology, genetics, cellular and animal models, small molecule and immuno-therapeutics and clinical research. MRC and UCL have jointly invested £30 million in provision of a dedicated new building in central London for the Institute supporting the vision to expand research in protein misfolding and aggregation in neurodegenerative disease. About the role You will work under the supervision of Dr Gargi Banerjee (grant holder) within a research programme titled “The expanded prion paradigm and amyloid-beta diseases”. This research explores recent clinical observations which show that the amyloid-beta protein, which causes Alzheimer’s disease and cerebral amyloid angiopathy (CAA) can behave as a prion, and cause newly identified iatrogenic diseases in people exposed to cadaveric tissues earlier in life. The MRC Prion Unit at UCL has led research in this area, with high profile publications in journals including Nature and Nature Medicine. You will primarily support a new longitudinal cohort study, which will review whether people previously treated with cadaveric human growth hormone have early signs of Alzheimer’s disease or CAA. You will contribute to clinical data collection and analysis for this study, and to the study’s patient and public engagement/involvement (PPI) activities, which includes the creation of a peer-support group for this cohort. An Honorary Clinical contract will be sought from UCLH, and any other Trusts where the postholder may provide input, for which a DBS check will be required. The post is available and is funded by the Medical Research Council for one year. There may be a possibility of a one-year extension, but this cannot be guaranteed at this stage. If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact HR (p.petmeza@ucl.ac.uk). A full job description and person specification for this role can be accessed below. To apply, please upload a current CV, complete the online application form, and use the supporting statement section or upload a cover letter to outline how you meet the essential and desirable criteria for the role. Please do not upload any additional attachments as these will not be considered by the selection panel. About you You will have a medical degree (MBBS, MB BCh, or equivalent) and be GMC registered with a license to practice (or be eligible for full GMC registration). An interest in pursuing translational clinical research in neurology, the ability to work co-operatively in a multidisciplinary team, and technical writing are also essential for this role. You will be a registered medical practitioner permitted to practise in the UK and have completed general medical training. This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa. What we offer The starting salary will be £57,488 per annum (CL7.4 and StR Level 3) or £57,853 per annum (RDPS Nodal Point 3), inclusive of London Allowance. As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

• 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
• Additional 5 days’ annual leave purchase scheme
• Defined benefit career average revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket loan
• Immigration loan
• Relocation scheme for certain posts
• On-Site nursery
• On-site gym
• Enhanced maternity, paternity and adoption pay
• Employee assistance programme: Staff Support Service
• Discounted medical insurance

Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more. We will consider applications to work on a part-time, flexible, and job share basis wherever possible. This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information. Our commitment to Equality, Diversity and Inclusion The Institute of Prion Diseases believes the greatest progress in our research mission can be achieved through a workplace that embraces diversity and inclusion. In 2021 we were awarded our Athena Swan Bronze status in recognition of our long-term plan committing to change to achieve highest level of excellence in promoting equality. The principles of Athena Swan are now fully embedded in all of our activities in order to develop a culture in which all our staff and students can flourish. We will continue to critically assess our efforts and impacts and make improvements to provide an environment that encourages inclusion and scientific excellence for many years to come. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce; these include people from Black, Asian and ethnic minority backgrounds, disabled people, LGBTQI+ and gender diverse people in all roles, and women in Grade 9 and 10 roles.